All Chronic Leukemia CML and CLL

Chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL) are two types of chronic leukemia, which are cancers that affect the blood and bone marrow and develop slowly over time. Chronic myeloid leukemia (CML) is a type of leukemia that originates in the bone marrow's myeloid cells, which are responsible for producing red blood cells, white blood cells, and platelets. In CML, there is an abnormal genetic change called the Philadelphia chromosome, which results in the overproduction of immature white blood cells called granulocytes. These leukemia cells gradually accumulate in the bone marrow and blood, interfering with normal blood cell production.