Uterine cancer, also known as endometrial cancer, originates in the lining of the uterus. It is the most common cancer of the female reproductive system. Symptoms may include abnormal vaginal bleeding, particularly after menopause or between periods, pelvic pain, or pain during intercourse. Risk factors include hormonal imbalances, obesity, diabetes, and a history of endometrial hyperplasia or estrogen therapy without progesterone. Diagnosis involves imaging tests, endometrial biopsy, or dilation and curettage. Treatment typically involves surgery to remove the uterus and possibly other affected tissues, followed by radiation or chemotherapy.


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